Article
When the message goes awry: disease-producing mutations that influence mRNA content and performance.
Cell - 16 Nov 2001
Mendell J T, Dietz H C
Abstract excerpt
Mutations that cause disease commonly occur in the coding sequence and directly influence protein structure and function. However, many diseases result from mutations that influence various aspects of mRNA metabolism, including processing, export, stability, and translational control.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.