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Article

Characterization of surface antigen from Lyme disease spirochete Borrelia burgdorferi.

Biochemical and biophysical research communications - 30 Nov 2001

Jones K, Guidry J, Wittung-Stafshede P

Abstract excerpt

Borrelia burgdorferi, the Lyme disease spirochete, possesses a surface protein, VlsE (variable major protein-like sequence, expressed), that undergoes antigenic variation. Unlike conserved regions of other proteins involved in antigenic variation, the most conserved invariable region of VlsE is immunodominant in Lyme-disease patients. Physicochemical analyses of pure recombinant VlsE yielded the following...

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Identifiers

PMID: 11716485
DOI: 10.1006/bbrc.2001.5983

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Characterization of surface antigen from Lyme disease spirochete Borrelia burgdorferi.PMID 11716485Read ↗

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