Article
Interaction of lyssaviruses with the low-affinity nerve-growth factor receptor p75NTR.
The Journal of general virology - 1 Dec 2001
Tuffereau Christine, Desmézières Emmanuel, Bénéjean Jacqueline, Jallet Corinne, Flamand Anne, Tordo Noël, Perrin Pierre
Abstract excerpt
The low-affinity nerve-growth factor receptor p75NTR interacts in vitro with the rabies virus (RV) glycoprotein and serves as a receptor for RV. The Lyssavirus genus comprises seven genotypes (GTs) of rabies and rabies-related viruses. The ability of p75NTR to interact with the glycoprotein of representative lyssaviruses from each GT was investigated. This investigation was based on a specific binding assay...
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