Article
Primary systemic anaplastic large-cell lymphoma (CD30+): advances in biology and current therapeutic approaches.
Clinical lymphoma - 1 Jun 2001
Fiorani C, Vinci G, Sacchi S, Bonaccorsi G, Artusi T
Abstract excerpt
In 1985, Stein et al demonstrated the expression of the lymphoid activation antigen CD30/Ki by neoplastic cells. Fifteen years after the first description, anaplastic large-cell lymphomas (ALCL) are now thought to be a heterogeneous group in terms of their clinical, morphologic, phenotypic, cytogenetic, and molecular biology features. However, on the basis of a specific genetic anomaly and expression of a...
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