Article
The N-terminus of histone H2B, but not that of histone H3 or its phosphorylation, is essential for chromosome condensation.
The EMBO journal - 15 Nov 2001
de la Barre A E, Angelov D, Molla A, Dimitrov S
Abstract excerpt
We have studied the role of individual histone N-termini and the phosphorylation of histone H3 in chromosome condensation. Nucleosomes, reconstituted with histone octamers containing different combinations of recombinant full-length and tailless histones, were used as competitors for chromosome assembly in Xenopus egg extracts. Nucleosomes reconstituted with intact octamers inhibited chromosome condensation as...
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