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Article

Chronic long-term nitrate therapy: possible cytogenetic effect in humans?

Mutagenesis - 1 Nov 2001

Andreassi M G, Picano E, Del Ry S, Botto N, Colombo M G, Giannessi D, Lubrano V, Vassalle C, Biagini A

Abstract excerpt

Nitrates act as donors of nitric oxide (NO), a molecule with a recognized potential for genotoxicity. In order to assess whether chronic long-term nitrate therapy may increase genotoxicity, we evaluated chromosomal damage in peripheral lymphocytes of 27 ischaemic patients undergoing chronic nitrate treatment for vertical line4 years (7.9 +/- 3.1, mean +/- SD) and 18 age- and sex-matched subjects without any...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11682643
DOI: 10.1093/mutage/16.6.517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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