Parents concordant for major depressive disorder and the effect of psychopathology in offspring

Abstract excerpt

BACKGROUND: Concordance for major depressive disorder (MDD) between parents could happen for different reasons. Regardless of the origin and the frequency of the concordance, the effect on offspring of having two parents affected with MDD may be serious. The sex of the affected parent and offspring may also be a important risk factor for MDD in offspring. METHODS: We examined the increased risk of psychopathology...

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