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Article

What is the role of paternal genetic transmission on risk for PTSD and internalizing and externalizing disorders?

Psychological medicine - 10 Mar 2025

Amstadter Ananda B, Abrahamsson Linda, Hart James E, Sundquist Jan, Sundquist Kristina, Kendler Kenneth S

Abstract excerpt

BACKGROUND: We utilize a novel contrastive genetic-epidemiological method, the Maternal Half-Sibling Families with Discordant Fathers (MHSFDF) design, to examine cross-generational genetic transmission of posttraumatic stress disorder (PTSD) and related internalizing major depression (MD), and externalizing disorders: alcohol use disorder (AUD) and drug use disorder (DUD). METHODS: Using Swedish national...

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Identifiers

PMID: 40059839
DOI: 10.1017/S0033291725000546
PMCID: PMC12080631

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