Article
Impact of cancer predisposition and radiosensitivity on the population risk of radiation-induced cancers.
Radiation research - 1 Nov 2001
Sankaranarayanan K, Chakraborty R
Abstract excerpt
This paper provides a brief overview of the current evidence for cancer predisposition and for an increased sensitivity of individuals carrying such predisposing mutations to cancers induced by ionizing radiations. We also discuss the use of a Mendelian one-locus, two-allele autosomal dominant model for predicting the impact of cancer predisposition and increased radiosensitivity on the risk of radiation-induced...
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