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Article

Age-associated changes in cartilage matrix: implications for tissue repair.

Clinical orthopaedics and related research - 1 Oct 2001

Roughley P J

Abstract excerpt

The structure of the extracellular matrix of articular cartilage varies considerably with age. These changes are attributable to variations in molecular abundance and structure, and they can affect all the matrix components, but none more so than the proteoglycans. Some of these changes are attributable to variations in synthesis whereas others are attributable to variations in degradation, some of the changes...

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PMID: 11603700
DOI: 10.1097/00003086-200110001-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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