Article
Self-organization of a propulsive actin network as an evolutionary process.
Proceedings of the National Academy of Sciences of the United States of America - 25 Sept 2001
Maly I V, Borisy G G
Abstract excerpt
The leading edge of motile cells is propelled by polymerization of actin filaments according to a dendritic nucleation/array treadmilling mechanism. However, little attention has been given to the origin and maintenance of the dendritic array. Here we develop and test a population-kinetics model that explains the organization of actin filaments in terms of the reproduction of dendritic units. The life cycle of an...
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