Article
Understanding the mode of action of L-nucleosides as antiviral agents: a molecular modeling approach.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2000
Lee K, Chong Y, Chu C K
Abstract excerpt
Computer modeling studies have been performed on the several pairs of D- and L-nucleoside inhibitors with the HIV-1 RT model. Additionally, clinically important M184V mutation, which confers the viral resistance against 3TC and FTC, were studied by the same modeling system.
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