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Article

Aspects of biopsy procedures prior to preimplantation genetic diagnosis

20 Aug 2001

Abstract excerpt

Today, preimplantation genetic diagnosis (PGD) is offered in over 40 centres worldwide for an expanded range of genetic defects causing disease. This very early form of prenatal diagnosis involves the detection of affected embryos by fluorescent in situ hybridization (FISH) (sex determination or chromosomal defects) or by polymerase chain reaction (PCR) (monogenic diseases) prior to implantation. Genetic analysis...

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PMID: 11559914
DOI: 10.1002/pd.172

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