Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy?

Heart (British Cardiac Society) - 1 Oct 2001

Clarke N R, Kelion A D, Nixon J, Hilton-Jones D, Forfar J C

Abstract excerpt

OBJECTIVE: To assess whether the size of the cytosine-thymine-guanine (CTG) expansion mutation in myotonic dystrophy predicts progression of conduction system disease and cardiac events. DESIGN: Longitudinal study involving ECG and clinical follow up over (mean (SD)) 4.8 (1.8) and 6.2 (1.9) years, respectively, of patients stratified by CTG expansion size (E0 to E4). PATIENTS: 73 adult patients under annual...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Cytosine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Death, Sudden, Cardiac

Share to Defibrillators, Implantable

Share to Echocardiography

Share to Myotonic Dystrophy

Share to Thymine

Share to Trinucleotide Repeat Expansion

Source

Open in PubMed Open full text

Identifiers

PMID: 11559681
DOI: 10.1136/heart.86.4.411
PMCID: PMC1729946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy?PMID 11559681Read ↗

Association Between Mutation Size and Cardiac Involvement in Myotonic Dystrophy Type 1: An Analysis of the DM1-Heart Registry.Semantic proximity Read ↗

Relationships among electrophysiological findings and clinical status, heart function, and extent of DNA mutation in myotonic dystrophy.Semantic proximity Read ↗

Relation of CTG expansion and clinical variables to electrocardiogram conduction abnormalities and sudden death in patients with myotonic dystrophy.Semantic proximity Read ↗

Survival and CTG repeat expansion in adults with myotonic dystrophy type 1Semantic proximity Read ↗

Correlation between cardiac involvement and CTG trinucleotide repeat length in myotonic dystrophySemantic proximity Read ↗

Heart rate variability declines with increasing age and CTG repeat length in patients with myotonic dystrophy type 1.Semantic proximity Read ↗

Myotonic dystrophy: correlation of clinical symptoms with the size of the CTG trinucleotide repeat.Semantic proximity Read ↗

Preliminary Findings on CTG Expansion Determination in Different Tissues from Patients with Myotonic Dystrophy Type 1.Semantic proximity Read ↗

Larger expansions of the CTG repeat in muscle compared to lymphocytes from patients with myotonic dystrophy.Semantic proximity Read ↗

Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients.Semantic proximity Read ↗

Size of the unstable CTG repeat sequence in relation to phenotype and parental transmission in myotonic dystrophy.Semantic proximity Read ↗

Clinical characteristics of myotonic dystrophy type 1 patients with small CTG expansions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.