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Article

Characterization of subsets of human spermatozoa at different stages of maturation: implications in the diagnosis and treatment of male infertility

1 Sept 2001

Abstract excerpt

BACKGROUND: Reactive oxygen species (ROS)-induced damage of membrane phospholipids and DNA in human spermatozoa has been implicated in the pathogenesis of male infertility. In this study, variations in ROS production, DNA structure (as measured by the sperm chromatin structure assay) and lipid composition, were studied in human spermatozoa at different stages of maturation. METHODS: Sperm subsets were isolated by...

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PMID: 11527898
DOI: 10.1093/humrep/16.9.1912

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