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Article

Corticosteroids alter the differentiated phenotype of articular chondrocytes.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 2001

Fubini S L, Todhunter R J, Burton-Wurster N, Vernier-Singer M, MacLeod J N

Abstract excerpt

Experimental evidence suggests that recommended dosages of some corticosteroids used clinically as antiinflammatory agents for treating arthropathies damage articular cartilage, but low dosages may be chondroprotective. The purpose of this study was to evaluate how different concentrations of methylprednisolone affect chondrocyte function and viability. Articular cartilage and chondrocytes were obtained from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11518280
DOI: 10.1016/S0736-0266(00)00060-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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