Article
Feedback regulation of glucose transporter gene transcription in Kluyveromyces lactis by glucose uptake.
Journal of bacteriology - 1 Sept 2001
Milkowski C, Krampe S, Weirich J, Hasse V, Boles E, Breunig K D
Abstract excerpt
In the respirofermentative yeast Kluyveromyces lactis, only a single genetic locus encodes glucose transporters that can support fermentative growth. This locus is polymorphic in wild-type isolates carrying either KHT1 and KHT2, two tandemly arranged HXT-like genes, or RAG1, a low-affinity transporter gene that arose by recombination between KHT1 and KHT2. Here we show that KHT1 is a glucose-induced gene encoding...
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