Article
Identification of a novel protein encoded by the latency-related gene of bovine herpesvirus 1.
Journal of neurovirology - 1 Dec 2007
Meyer Florencia, Perez Sandra, Jiang Yunquan, Zhou You, Henderson Gail, Jones Clinton
Abstract excerpt
The latency-related (LR) RNA encoded by bovine herpesvirus 1 (BHV-1) is abundantly expressed and alternatively spliced in trigeminal ganglia. A mutant BHV-1 strain that contains three stop codons at the beginning of LR open reading frame (ORF)-2 (LR mutant virus) does not express ORF-2 or an adjacent reading frame that lacks an initiating ATG (RF-C). Calves latently infected with wild-type (wt) BHV-1, but not...
Topics
- Antibodies, Viral
- Genes, Viral
- Herpesviridae Infections
- Herpesvirus 1, Bovine
- Microscopy, Confocal
- Mutation
- Open Reading Frames
- Tumor Cells, Cultured
- Viral Fusion Proteins
- Viral Proteins
- Virus Activation
