Article
Multiple points of intervention in the prevention of cancer and other mutation-related diseases.
Mutation research - 1 Sept 2001
De Flora S, Izzotti A, D'Agostini F, Balansky R M, Noonan D, Albini A
Abstract excerpt
Multiple points of intervention are the target for dietary and pharmacological interventions aimed at preventing cancer and other diseases in which mutations in somatic cells play a pathogenetic role. For instance, our studies showed that DNA adducts can be consistently detected in arterial smooth muscle cells from human atherosclerotic lesions. Their levels were significantly correlated with the occurrence of...
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