Article
Ferrets as a transmission model for influenza: sequence changes in HA1 of type A (H3N2) virus.
The Journal of infectious diseases - 1 Sept 2001
Herlocher M L, Elias S, Truscon R, Harrison S, Mindell D, Simon C, Monto A S
Abstract excerpt
Ferrets were used as an animal model to study whether controlled transmission of type A influenza is similar to human transmission when sequence changes in HA1 are used as the outcome. Ferrets were infected initially with A/Sydney/5/97 (H3N2) or A/LA/1/87 (H3N2) intranasally, and transmission chains were established by housing infected ferrets with noninfected ferrets with no influenza antibody titer against the...
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