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Exploring the transcriptome of the malaria sporozoite stage

7 Aug 2001

Abstract excerpt

Most studies of gene expression in Plasmodium have been concerned with asexual and/or sexual erythrocytic stages. Identification and cloning of genes expressed in the preerythrocytic stages lag far behind. We have constructed a high quality cDNA library of the Plasmodium sporozoite stage by using the rodent malaria parasite P. yoelii, an important model for malaria vaccine development. The technical obstacles...

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PMID: 11493695
DOI: 10.1073/pnas.171185198

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