Article
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
The American journal of pathology - 1 Aug 2001
Arbiser J L, Yeung R, Weiss S W, Arbiser Z K, Amin M B, Cohen C, Frank D, Mahajan S, Herron G S, Yang J, Onda H, Zhang H B, Bai X, Uhlmann E, Loehr A, Northrup H, Au P, Davis I, Fisher D E, Gutmann D H
Abstract excerpt
Angiomyolipomas are benign tumors of the kidney derived from putative perivascular epithelioid cells, that may undergo differentiation into cells with features of melanocytes, smooth muscle, and fat. To gain further insight into angiomyolipomas, we have generated the first human angiomyolipoma cell line by sequential introduction of SV40 large T antigen and human telomerase into human angiomyolipoma cells. These...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.