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Article

A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.

Nature genetics - 1 Aug 2001

Zhou B, Westaway S K, Levinson B, Johnson M A, Gitschier J, Hayflick S J

Abstract excerpt

Hallervorden-Spatz syndrome (HSS) is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Clinical features include extrapyramidal dysfunction, onset in childhood, and a relentlessly progressive course. Histologic study reveals iron deposits in the basal ganglia. In this respect, HSS may serve as a model for complex neurodegenerative diseases, such as Parkinson...

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Source

Identifiers

PMID: 11479594
DOI: 10.1038/ng572

Genes

PANK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.PMID 11479594Read ↗

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