Article
Affected sib-pair analysis in endometriosis.
Human reproduction update - 1 Jan 2000
Kennedy S, Bennett S, Weeks D E
Abstract excerpt
This paper (i) reviews the current clinical and molecular genetic data which strongly suggest that endometriosis has a genetic basis; (ii) outlines the general principles of affected-sib pair analysis; and (iii) describes the Oxford Endometriosis Gene (OXEGENE) Study which aims, using a positional cloning approach, to identify susceptibility genes involved in the development of the disease.
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