Article
Silver syndrome is not linked to any of the previously established autosomal dominant hereditary spastic paraplegia loci.
American journal of medical genetics - 22 Jul 2001
Patel H, Hart P E, Warner T, Allen I, Phillimore H E, Silver J R, Wood N W, Jeffery S, Patton M A, Crosby A H
Abstract excerpt
The hereditary spastic paraplegias are a clinically variable and genetically heterogeneous group of disorders characterized by progressive and lower limb spasticity and weakness. Silver syndrome (SS) is a particularly disabling autosomal dominant form of the disease in which there is associated wasting of the hand muscles. In view of the fact that genes for hereditary spastic paraplegia can produce highly...
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