Article
Computer-assisted methods for assessing strain relatedness in Candida albicans by fingerprinting with the moderately repetitive sequence Ca3.
Journal of clinical microbiology - 1 Jun 1990
Schmid J, Voss E, Soll D R
Abstract excerpt
When used to probe EcoRI-digested Candida albicans DNA, the moderately repetitive sequence Ca3 generated a Southern blot hybridization pattern which included 15 to 25 bands, depending upon the strain. The pattern was stable through 400 generations in each of three independent strains but variable between most of 46 unrelated tester strains, making it a very effective probe for discrimination between strains....
Topics
- Blotting, Southern
- Candida albicans
- DNA, Fungal
- Electronic Data Processing
- Female
- Genetic Variation
- Humans
- Immune Tolerance
- Iowa
- Male
- Mouth
- Repetitive Sequences, Nucleic Acid
