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Article

Homozygous deletion mutation of the parkin gene in patients with atypical parkinsonism.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 2001

Kuroda Y, Mitsui T, Akaike M, Azuma H, Matsumoto T

Abstract excerpt

Autosomal recessive juvenile parkinsonism (AR-JP) is characterised by homogenous clinical features and selective degeneration of nigral neurons. Recent progress in molecular genetic analyses of AR-JP has led to the identification of a novel ubiquitin-like protein, parkin, whose precise function still remains to be elucidated. Two unrelated Japanese families had levodopa unresponsive parkinsonism complicated with...

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Identifiers

PMID: 11459900
DOI: 10.1136/jnnp.71.2.231
PMCID: PMC1737499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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