Article
Silencing of antibody genes in plants with single-copy transgene inserts as a result of gene dosage effects.
Molecular genetics and genomics : MGG - 1 Jun 2001
De Wilde C, Podevin N, Windels P, Depicker A
Abstract excerpt
The stability of Fab antibody fragment expression during plant development was studied using two homozygous Arabidopsis thaliana lines that contain single copies of the transgenes. These lines exhibited expression characteristics that are typical for homology-based post-transcriptional gene silencing. Their developmental silencing profiles differed markedly, presumably due to the influence of the genomic context...
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