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Article

Interferon regulatory factor 1 promoter polymorphism and response to type 1 interferon.

Journal of cellular biochemistry. Supplement - 1 Jan 2001

Saito H, Tada S, Ebinuma H, Wakabayashi K, Takagi T, Saito Y, Nakamoto N, Kurita S, Ishii H

Abstract excerpt

The clinical success of interferon-treatment has been found to vary in different individuals. To explain this, we hypothesized that responses to type 1 interferons could be partly determined by interferon regulatory factor-1 gene transcription, because the latter is an important transcription factor in the interferon system. We demonstrated that the antiproliferative effect of type 1 interferons on human liver...

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PMID: 11455584
DOI: 10.1002/jcb.1084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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