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Article

Establishment and characterization of immortalized Schwann cells from murine model of Niemann-Pick disease type C (spm/spm).

Journal of the peripheral nervous system : JPNS - 1 Jun 2001

Watabe K, Ida H, Uehara K, Oyanagi K, Sakamoto T, Tanaka J, Garver W S, Miyawaki S, Ohno K, Eto Y

Abstract excerpt

Niemann-Pick disease type C (NPC) is characterized by an accumulation of unesterified cholesterol in the endosomal/lysosomal (E/L) system, resulting in progressive neurodegeneration and death during early childhood. To investigate the cellular pathomechanism of nervous system involvement in NPC,...

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Source

Identifiers

PMID: 11446388
DOI: 10.1046/j.1529-8027.2001.01012.x

Genes

NPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11446388-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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