Article
Cytokine promoter gene polymorphisms and idiopathic recurrent pregnancy loss.
Journal of reproductive immunology - 1 Jul 2001
Babbage S J, Arkwright P D, Vince G S, Perrey C, Pravica V, Quenby S, Bates M, Hutchinson I V
Abstract excerpt
Approximately one in 300 women experience recurrent pregnancy loss (RPL), the aetiology of which is unknown in at least 40% of cases. Previously, some studies have shown increased production of pro-inflammatory cytokines (tumour necrosis factor-alpha and interferon-gamma) and reduced production of anti-inflammatory cytokines (interleukin-10) by circulating blood lymphocytes isolated from these patients when...
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