Article
[T wave abnormalities on Holter monitoring of congenital long QT syndrome: phenotypic marker of a mutation of LQT2 (HERG)].
Archives des maladies du coeur et des vaisseaux - 1 May 2001
Lupoglazoff J M, Denjoy I, Berthet M, Hainque B, Vaksmann G, Klug D, Villain E, Lucet V, Guicheney P, Coumel P
Abstract excerpt
The two genes which code for the potassium channels, KCNQ1 and HERG, are responsible for the most common forms of the long QT syndrome, LQT1 and LQT2. Abnormalities of duration and morphology of the ventricular repolarisation are amongst the diagnostic criteria of this syndrome. The morphology of the T waves was studied by 24 hour Holter monitoring in 190 subjects with a long QT syndrome due to KCNQ1 (LQT1) [N =...
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