Article
Pre-Bötzinger neurons with preinspiratory discharges "in vivo" express NK1 receptors in the rat.
Journal of neurophysiology - 1 Jul 2001
Guyenet P G, Wang H
Abstract excerpt
Substance P stimulates respiration, in part by a direct action on the pre-Bötzinger complex (preBötC). This region of the medulla oblongata contains neurons that are strongly immunoreactive for the neurokinin-1 receptor (NK1R-ir), and a recent theory has postulated that these cells might be the adult form of excitatory interneurons that are essential for respiratory rhythmogenesis in neonates. Here we sought to...
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