Article
The double mechanism of incompatibility between lambda plasmids and Escherichia coli dnaA(ts) host cells.
Microbiology (Reading, England) - 1 Jul 2001
Glinkowska Monika, Konopa Grażyna, Węgrzyn Alicja, Herman-Antosiewicz Anna, Weigel Christoph, Seitz Harald, Messer Walter, Węgrzyn Grzegorz
Abstract excerpt
For plasmids derived from bacteriophage lambda, the initiation of bidirectional DNA replication from orilambda depends on the stimulation of transcription from the p(R) promoter by the host replication initiator protein DnaA. Certain Escherichia coli dnaA(ts) mutants cannot be transformed by wild-type lambda plasmids even at the temperature permissive to cell growth. This plasmid-host incompatibility appeared to...
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