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Article

Role of Nijmegen breakage syndrome protein in specific T-lymphocyte activation pathways.

Clinical and diagnostic laboratory immunology - 1 Jul 2001

García-Pérez M A, Allende L M, Corell A, Paz-Artal E, Varela P, López-Goyanes A, García-Martin F, Vázquez R, Sotoca A, Arnaiz-Villena A

Abstract excerpt

Nijmegen breakage syndrome (NBS) is a genetic disorder characterized by immunodeficiency, microcephaly, and "bird-like" facies. NBS shares some clinical features with ataxia telangiectasia (AT), including increased sensitivity to ionizing radiation, increased spontaneous and induced chromosome fragility, and strong predisposition to lymphoid cancers. The mutated gene that results in NBS codes for a novel...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11427422
DOI: 10.1128/CDLI.8.4.757-761.2001
PMCID: PMC96138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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