Human Thymic Stromal Lymphopoietin Preferentially Stimulates Myeloid Cells

doi:10.4049/jimmunol.167.1.336

Article

Human Thymic Stromal Lymphopoietin Preferentially Stimulates Myeloid Cells

1 Jul 2001

Abstract excerpt

The sequence of a novel hemopoietic cytokine was discovered in a computational screen of genomic databases, and its homology to mouse thymic stromal lymphopoietin (TSLP) suggests that it is the human orthologue. Human TSLP is proposed to signal through a heterodimeric receptor complex that consists of a new member of the hemopoietin family termed human TSLP receptor and the IL-7R alpha-chain. Cells transfected...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.