Article
The envelope of Mason-Pfizer monkey virus has immunosuppressive properties.
The Journal of general virology - 1 Jul 2001
Blaise Sandra, Mangeney Marianne, Heidmann Thierry
Abstract excerpt
We have demonstrated previously that the envelope protein of a murine retrovirus, Moloney murine leukaemia virus, has immunosuppressive properties in vivo. This property was manifested by the ability of the protein, when expressed by tumour cells normally rejected by engrafted mice, to allow the env-expressing cells to escape immune rejection and to proliferate. Here, it is shown that this property is not...
Topics
- Amino Acid Sequence
- Animals
- Immunocompetence
- Immunosuppression Therapy
- Mason-Pfizer monkey virus
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Molecular Sequence Data
- Mutation
- Retroviridae Infections
- Transfection
- Tumor Cells, Cultured
- Tumor Virus Infections
- Viral Envelope Proteins