Article
Livers from patients with apolipoprotein A-I amyloidosis are not suitable as "domino" donors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2001
Shaz B H, Lewis W D, Skinner M, Khettry U
Abstract excerpt
Orthotopic liver transplantation, by eliminating the major site of amyloidogenic protein synthesis, is currently the only definitive treatment of most hereditary amyloidoses. Because of the minimal parenchymal involvement, the explanted livers from familial amyloidotic polyneuropathy (FAP) patients have been transplanted into non-FAP patients in a "domino" fashion. The aim of this study was to evaluate the extent...
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