Article
Hereditary fibrinogen A alpha-chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation.
Blood - 15 Apr 2010
Stangou Arie J, Banner Nicholas R, Hendry Bruce M, Rela Mohamed, Portmann Bernard, Wendon Julia, Monaghan Mark, Maccarthy Philip, Buxton-Thomas Muriel, Mathias Christopher J, Liepnieks Juris J, O'Grady John, Heaton Nigel D, Benson Merrill D
Abstract excerpt
Variants of fibrinogen A alpha-chain (AFib) cause the most common type of hereditary renal amyloidosis in Europe and, possibly, the United States as well. Variant fibrinogen is produced in the liver, and solitary renal allografts fail within 1 to 7 years with recurrent amyloidosis. We assessed 22...
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