Article
Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation.
Infection and immunity - 1 Jul 2001
Pannekoek Y, van der Ende A, Eijk P P, van Marle J, de Witte M A, Ossewaarde J M, van den Brule A J, Morré S A, Dankert J
Abstract excerpt
To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.