Article
Variations in the surface proteins and restriction enzyme systems of Mycoplasma pulmonis in the respiratory tract of infected rats.
Molecular microbiology - 1 May 2001
Gumulak-Smith J, Teachman A, Tu A H, Simecka J W, Lindsey J R, Dybvig K
Abstract excerpt
Restriction and modification (R-M) systems are generally thought to protect bacteria from invasion by foreign DNA. This paper proposes the existence of an alternative role for the phase-variable R-M systems encoded by the hsd loci of Mycoplasma pulmonis. Populations of M. pulmonis cells that arose during growth in different environments were compared with respect to R-M activity and surface antigen production....
Topics
- Animals
- DNA Restriction Enzymes
- Female
- Genetic Variation
- Membrane Proteins
- Mycoplasma
- Mycoplasma Infections
- Rats
- Rats, Inbred F344
- Respiratory Tract Infections