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Article

Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.

Biochemical and biophysical research communications - 6 Apr 2001

Kamsteeg E J, Deen P M

Abstract excerpt

Aquaporin-2 (AQP2) water channel mutations cause autosomal recessive and dominant nephrogenic diabetes insipidus (NDI). Expressed in oocytes, a mutant in dominant (AQP2-E258K), but not in recessive (AQP2-R187C), NDI conferred a specific dominant-negative effect on wild-type (wt) AQP2 water permeability (Pf) only at low expression levels. Since at these levels, the yield of conventional-isolated plasma membranes...

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Source

Identifiers

PMID: 11401515
DOI: 10.1006/bbrc.2001.4629

Genes

AQP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.PMID 11401515Read ↗

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