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Article

Physical interaction of CcmC with heme and the heme chaperone CcmE during cytochrome c maturation.

The Journal of biological chemistry - 31 Aug 2001

Ren Q, Thony-Meyer L

Abstract excerpt

Biogenesis of c-type cytochromes requires the covalent attachment of heme to the apoprotein. In Escherichia coli, this process involves eight membrane proteins encoded by the ccmABCDEFGH operon. CcmE binds heme covalently and transfers it to apocytochromes c in the presence of other Ccm proteins. CcmC is necessary and sufficient to incorporate heme into CcmE. Here, we report that the CcmC protein directly...

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Identifiers

PMID: 11384983
DOI: 10.1074/jbc.M103058200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Physical interaction of CcmC with heme and the heme chaperone CcmE during cytochrome c maturation.PMID 11384983Read ↗

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