Article
Cerebral phosphate metabolism in first-degree relatives of patients with schizophrenia.
The American journal of psychiatry - 1 Jun 2001
Klemm S, Rzanny R, Riehemann S, Volz H P, Schmidt B, Gerhard U J, Filz C, Schönberg A, Mentzel H J, Kaiser W A, Blanz B
Abstract excerpt
OBJECTIVE: Most phosphorus-31 magnetic resonance spectroscopy ((31)P-MRS) studies have described measures of lower membrane anabolism or greater catabolism in the frontal lobes of patients with schizophrenia. The purpose of the present study was to evaluate whether these findings can also be detected in young subjects at genetic risk for schizophrenia. METHOD: Fourteen children and siblings of patients with...
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