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Article

ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture.

International journal of radiation oncology, biology, physics - 1 Jun 2001

Tribius S, Pidel A, Casper D

Abstract excerpt

PURPOSE: Glioblastoma multiforme (GBM) is one of the malignancies most resistant to radiation therapy. In contrast, cells derived from individuals with ataxia telangiectasia (AT), possessing mutations in the ATM gene, demonstrate increased sensitivity to ionizing radiation. Using a collection of...

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Source

Identifiers

PMID: 11380241
DOI: 10.1016/s0360-3016(01)01489-4

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11380241-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture.PMID 11380241Read ↗

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ATM Expression Is Elevated in Established Radiation-Resistant Breast Cancer Cells and Improves DNA Repair EfficiencySemantic proximity Read ↗

[DNA repair and tumour radiosensitivity: focus on ATM gene].Semantic proximity Read ↗

Radiosensitivity and TP 53, EGFR amplification and LOH10 analysis of primary glioma cell cultures.Semantic proximity Read ↗

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damageSemantic proximity Read ↗

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Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity.Semantic proximity Read ↗

The p53-mediated DNA damage response to ionizing radiation in fibroblasts from ataxia-without-telangiectasia patients.Semantic proximity Read ↗

Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines.Semantic proximity Read ↗

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