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Article

Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme.

BMC biochemistry - 1 Jan 2001

Marshall B, Keskin D B, Mellor A L

Abstract excerpt

BACKGROUND: The tryptophan catabolizing enzyme, indoleamine 2,3, dioxygenase (IDO) is one of two mammalian enzymes, which can catabolize the rarest essential amino acid, tryptophan. IDO is inducible by cytokines such as interferon-gamma and plays a role in inflammation and maternal tolerance of fetal allografts, although its exact mode of action is unclear. Therefore, we investigated the circumstances under which...

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Identifiers

PMID: 11375052
DOI: 10.1186/1471-2091-2-5
PMCID: PMC31925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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