Article
Vital involvement of a natural killer cell activation receptor in resistance to viral infection.
Science (New York, N.Y.) - 4 May 2001
Brown M G, Dokun A O, Heusel J W, Smith H R, Beckman D L, Blattenberger E A, Dubbelde C E, Stone L R, Scalzo A A, Yokoyama W M
Abstract excerpt
Natural killer (NK) cells are lymphocytes that can be distinguished from T and B cells through their involvement in innate immunity and their lack of rearranged antigen receptors. Although NK cells and their receptors were initially characterized in terms of tumor killing in vitro, we have determined that the NK cell activation receptor, Ly-49H, is critically involved in resistance to murine cytomegalovirus in...
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