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Article

Response of Bacillus subtilis to cerulenin and acquisition of resistance.

Journal of bacteriology - 1 May 2001

Schujman G E, Choi K H, Altabe S, Rock C O, de Mendoza D

Abstract excerpt

Cerulenin is a fungal mycotoxin that potently inhibits fatty acid synthesis by covalent modification of the active site thiol of the chain-elongation subtypes of beta-ketoacyl-acyl carrier protein (ACP) synthases. The Bacillus subtilis fabF (yjaY) gene (fabF(b)) encodes an enzyme that catalyzes the condensation of malonyl-ACP with acyl-ACP to extend the growing acyl chain by two carbons. There were two mechanisms...

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Identifiers

PMID: 11325930
DOI: 10.1128/JB.183.10.3032-3040.2001
PMCID: PMC95202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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