Article
Loci on murine chromosomes 7 and 13 that modify the phenotype of the NOA mouse, an animal model of atopic dermatitis.
Journal of human genetics - 1 Jan 2001
Watanabe O, Tamari M, Natori K, Onouchi Y, Shiomoto Y, Hiraoka I, Nakamura Y
Abstract excerpt
The NOA (Naruto Research Institute Otsuka Atrichia) mouse is an animal model of allergic or atopic dermatitis, a condition characterized by ulcerative skin lesions with accumulation of mast cells and increased serum IgE. We reported earlier that a major gene responsible for dermatitis in the NOA mouse lay in the middle of chromosome 14, and that the incidence of disease clearly differed according to parental...
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