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Article

A Novel Member of the Ig Superfamily,turtle, is a CNS-Specific Protein Required for Coordinated Motor Control

1 May 2001

Abstract excerpt

We describe here the cloning and functional characterization of a neural-specific novel member of the Ig superfamily, turtle (tutl), with a structure of five Ig C2-type domains, two fibronectin type III domains, and one transmembrane region. Alternative splicing of the tutl gene produces at least four Tutl isoforms, including two transmembrane proteins and two secreted proteins, with primary structures closely...

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PMID: 11312296
DOI: 10.1523/jneurosci.21-09-03113.2001

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